Search on: LIPOPROTEINS, VLDL 
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Descriptor English:   Lipoproteins, VLDL 
Descriptor Spanish:   Lipoproteínas VLDL 
Descriptor Portuguese:   Lipoproteínas VLDL 
Synonyms English:   Prebeta-Lipoproteins
Very-Low-Density Lipoproteins  
Tree Number:   D10.532.599
D12.776.521.622
Definition English:   A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues. 
Indexing Annotation English:   hypoprebetalipoproteinemia = LIPOPROTEINS, VLDL /blood (IM) + HYPOLIPOPROTEINEMIAS (IM); /defic: consider also HYPOLIPOPROTEINEMIAS
History Note English:   74(72); VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1972-95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   8253 
Unique Identifier:   D008079 

Occurrence in VHL:
 

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